Comprehensive strategy including prophylactic mupirocin to reduce Staphylococcus aureus colonization and infection in high-risk neonates
نویسندگان
چکیده
منابع مشابه
Targeting surface protein SasX by active and passive vaccination to reduce Staphylococcus aureus colonization and infection.
SasX is a recently described surface protein of Staphylococcus aureus that is linked to the epidemic success of hospital-associated methicillin-resistant clones, in particular in Asia. It enhances nasal colonization and virulence in skin and lung infection models. Here, we evaluated the potential of SasX as a vaccine component in passive and active immunization efforts using mouse infection mod...
متن کاملInfection and colonization by Staphylococcus aureus in a high risk nursery of a Brazilian teaching hospital.
Neonates are susceptible to nosocomial infections due to immunological immaturity, prolonged hospital stay and the use of invasive procedures. We evaluated the incidence of infections and the prevalence of colonization by MRSA (Methicillin-resistant Staphylococcus aureus) and MSSA (Methilin-susceptible Staphylococcus aureus), as well as colonization risk factors. Staphylococcal infections were ...
متن کاملMupirocin Resistance in Methicillin Resistant Staphylococcus Aureus
Mupirocin is the topical antimicrobial agent which is used for the treatment of methicillin resistant Staphylococcus aureus (MRSA). However the prevalence of mupirocin resistance in MRSA has increased with the extensive and widespread use of this agent in hospital settings. The present study was attempted to evaluate the low level and high level resistance to mupirocin in MRSA isolates by diffe...
متن کاملMupirocin Resistance in Methicillin Resistant Staphylococcus Aureus
Mupirocin is the topical antimicrobial agent which is used for the treatment of methicillin resistant Staphylococcus aureus (MRSA). However the prevalence of mupirocin resistance in MRSA has increased with the extensive and widespread use of this agent in hospital settings. The present study was attempted to evaluate the low level and high level resistance to mupirocin in MRSA isolates by diffe...
متن کاملStaphylococcus aureus colonization and infection in New York State prisons.
Methicillin-resistant Staphylococcus aureus is increasingly responsible for staphylococcal outbreaks in prison. There is limited information on the source of the outbreak strains, risk factors for infection, and transmission of these strains within a prison. We conducted a survey to determine the prevalence of nasal colonization with S. aureus in 2 New York State prisons. S. aureus isolates fro...
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ژورنال
عنوان ژورنال: Journal of Perinatology
سال: 2012
ISSN: 0743-8346,1476-5543
DOI: 10.1038/jp.2012.102